Factors Associated With Functional Decline in Hand and Hip/Knee Osteoarthritis After One Year: Data From a Population?Based Study

Objective To investigate factors that together with hand or hip/knee osteoarthritis (OA) could contribute to functional decline over a year’s time in elderly individuals. Methods The data of 1,886 individuals between ages 65 and 85 years prospective, observational population-based study 12–18 months follow-up the context European Project on Osteoarthritis were analyzed. outcome measures self-reported decline, evaluated using minimum clinically important difference 4 Australian/Canadian Hand OA Index 2 Western Ontario McMaster Universities physical function subscales, both normalized 0–100. Using regression models adjusted for sex, age, country, education level, baseline considered clinical OA, pain, analgesic/antiinflammatory medications, comorbidities, social isolation, income, walking time, grip strength, activity medical/social care. Results After year, 453 participants identified as having worse functionality 1,389 not worse. anxiety, strength risk decline; pain was confounder effect OA. Analgesic/antiinflammatory medications mediated combined plus 554 classified 1,291 persons who Peripheral artery disease, obesity, cognitive impairment other factors. Conclusion Study findings showed emotional status chronic conditions, affects decline.